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Best ICSI Clinics in United States

Top ICSI Clinics in United States

Clinics with the highest ratings and verified quality care in this region.

United States
star 5.0 (734)

Male Fertility and Peyronie’s Clinic

Male Fertility and Peyronie's Clinic is a specialized male infertility and Peyronie's disease clinic located in Orem, Utah, USA, serving patients from all 50 states and 16 countries, and specializing in comprehensive male reproductive health and penile curvature disorders; the center offers expert evaluation and treatment for Peyronie's disease—including over 2,000 Xiaflex injections, penile ultrasounds, and the novel RestoreX traction device—alongside the nation’s highest volume of vasectomy reversals (vasovasostomy and epididymovasostomy), cost‑effective microTESE for non‑obstructive azoospermia performed under local anesthesia, and a full suite of male fertility services such as semen analysis, cryopreservation, varicocelectomy, and advanced sperm extraction techniques; founded by Dr. Landon Trost, former head of male infertility at the Mayo Clinic, and supported by a multidisciplinary team that includes former Mayo PA Joshua Savage, DNP‑C Klinton Brearton, NP‑Cs Riley Warner, Chelsea Dudley, Nicholaus Haws, and CRNA Jacob Hunsaker, the clinic combines world‑class outcomes—highlighted by an 8‑fold improvement in pregnancy rates with the ReVas technique and published success‑rate estimates for reversals—with affordable pricing, extensive research‑driven innovations, and patient‑centered support such as free customized treatment recommendations, video consultations, insurance estimates, and dedicated assistance for interstate and international travelers.

Virginia, Richmond
star 4.9 (28)

Acupuncture Infertility Care

Acupuncture Infertility Care is a Traditional Chinese Medicine fertility clinic located in Richmond, specializing in acupuncture‑based treatment for women facing infertility and conception challenges; the practice, led by licensed acupuncturist Porter Nilsson, Lic Ac MSOM, offers comprehensive acupuncture to correct constitutional imbalances, targeted stress‑reduction strategies, and integrative support for Assisted Reproductive Technologies such as IVF, claiming a roughly 50 % increase in successful full‑term pregnancies when combined with ART, and also provides specialized protocols for PCOS, endometriosis, unexplained infertility, and male factor issues along with educational resources on fertility stress, parenting classes, and personalized patient forms, distinguishing it as Richmond’s only practice devoted exclusively to fertility care with a unique focus on stress as a key obstacle, and a professional, compassionate team that delivers one‑on‑one consultations, ongoing monitoring, and easy access via phone or text (804‑938‑6457) to ensure patients receive holistic and family‑centered support throughout the entire conception journey.

United States
star 4.9 (97)

Shady Grove Fertility in Spring-Woodlands, TX

Shady Grove Fertility is a reproductive‑medicine clinic with nationwide locations across the United States—including major centers in Richmond, VA; Houston, TX; and Philadelphia, PA—specializing in IVF, egg‑freezing, IUI, gestational carrier programs, LGBTQ+ family building, and advanced treatments for male infertility, recurrent pregnancy loss, and unexplained infertility; the clinic offers a full suite of services such as fertility testing, personalized treatment planning, shared‑risk IVF guarantees (including a 100 % refund if a cycle does not result in a live birth), comprehensive insurance acceptance, flexible financing, and on‑site mental‑health and counseling support; with more than 100,000 babies born, a reported 96 % patient recommendation rate, and a baby delivered on average every two hours, Shady Grove highlights its proven success while emphasizing a warm, relationship‑based approach delivered by a multidisciplinary team of highly respected physicians, embryologists, nurses, and support staff who prioritize empathy, transparency, and continuous innovation; patients also benefit from extensive educational resources, regular seminars, and a variety of virtual and in‑person support groups designed to address emotional, financial, and community needs throughout their family‑building journey.

United States
star 4.9 (38)

Selma Amrane, M.D.

Shady Grove Fertility is a comprehensive reproductive medicine clinic located across the United States with 58 locations, specializing in IVF, IUI, egg freezing, LGBTQ + family building, gestational carrier and donor‑egg programs, and advanced treatments for age‑related and male infertility. The center offers a full suite of services including fertility testing, personalized treatment planning, shared‑risk IVF guarantees (a 100 % refund if a cycle does not result in a live birth), extensive insurance acceptance, flexible financing, and on‑site mental‑health counseling, while its warm, relationship‑based support staff guides patients through every step of the journey. With more than 100,000 babies born, a baby delivered every two hours, and 96 % of patients recommending the clinic, Shady Grove demonstrates nationally recognized success rates. Its team of world‑renowned physicians, embryologists, nurses and allied professionals collaborates in a culture of continuous innovation and compassionate care, supported by regular support groups, educational seminars, and a robust online resource library, ensuring patients receive both cutting‑edge medical expertise and holistic emotional support throughout their family‑building experience.

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United States
star 4.9 (55)

Reproductive Health and Wellness Center

RMA Southern California is a reproductive endocrinology and infertility clinic located in Orange County, California, with satellite offices in Laguna Hills, Mission Viejo, Newport Beach, Los Angeles, San Francisco and San Diego, specializing in comprehensive, patient‑first fertility care that includes IVF, IUI, egg freezing, third‑party reproduction, pre‑implantation genetic testing, LGBTQ+ family building and advanced male and female fertility diagnostics. Unique to the region, RMA Southern California houses in‑house embryology laboratories and surgical suites, allowing all testing, embryo screening and treatment cycles to be completed under one roof, which streamlines care and reduces coordination delays. The clinic’s double board‑certified reproductive endocrinologists, Dr. Sanaz Ghazal and Dr. Marcus Rosencrantz, lead a multidisciplinary team that also features certified genetic counselors Amber Gamma and Allison “Alleigh” Boyd, providing personalized treatment plans and compassionate support. Although specific success rates are not disclosed, the clinic emphasizes proven results and offers same‑week appointments, telehealth consultations, a dedicated financial counseling service that navigates insurance, financing and discount programs, a free multilingual language line, and a robust patient portal for ongoing education and support throughout the fertility journey.

United States
star 4.8 (30)

Jaimin S. Shah, M.D.

Shady Grove Fertility is a reproductive endocrinology and infertility clinic located in Spring‑Woodlands and Houston‑Memorial City, Texas, specializing in comprehensive IVF and fertility preservation care. The center offers a full spectrum of services including in‑vitro fertilization, donor egg and sperm programs, pre‑implantation genetic testing, oocyte cryopreservation, embryo transfer simulation training, telehealth consultations, and dedicated mental‑health counseling for patients navigating the emotional aspects of treatment. Led by Dr. Jaimin S. Shah, M.D., a board‑certified OB/GYN and REI fellow trained at Harvard Medical School and Beth Israel Deaconess, the team combines cutting‑edge research—reflected in dozens of peer‑reviewed publications and presentations at ASRM, PCRS, and ESHRE—with a compassionate, patient‑centered approach that emphasizes clear communication, shared decision‑making, and individualized care plans. Recognized as a 2025 Houstonia Magazine Top Doctor and a Texas Monthly Rising Star, Dr. Shah and his staff provide a supportive environment featuring same‑day appointments, multilingual staff, and comprehensive educational resources, contributing to consistently high satisfaction scores and strong pregnancy outcomes reported by patients.

United States
star 4.8 (42)

Shady Grove Fertility at Solana Beach

Shady Grove Fertility is a leading reproductive medicine clinic headquartered in the United States with a network of 58 locations nationwide, specializing in comprehensive IVF and family‑building services for diverse patients. The center offers a full spectrum of treatments including in‑vitro fertilization, frozen‑embryo transfer, intrauterine insemination, egg freezing, gestational carrier cycles, donor‑egg and embryo programs, and LGBTQ+‑focused options such as reciprocal IVF, while also providing advanced protocols for age‑related and male factor infertility. Unique features include a pioneering “shared‑risk” IVF program that guarantees a full refund if a cycle does not result in a live birth, acceptance of all major insurances, flexible financing, and a proven track record of over 100,000 babies born with 96% of patients recommending the clinic. The multidisciplinary team of world‑renowned physicians, embryologists, nurses and compassionate support staff delivers a relationship‑based, personalized approach, reinforced by warm, welcoming staff at every level. Extensive patient‑support services encompass mental‑health counseling, numerous virtual and in‑person support groups (including singles, general infertility, donor‑recipient, pregnancy‑loss and queer family‑building groups), educational seminars, and a dedicated support team that guides patients through odds, costs and options, ensuring a holistic and hopeful journey toward parenthood.

Texas, San Antonio
star 4.8 (106)

Pozitivf Fertility

Pozitivf Fertility is a high‑quality, affordable IVF and reproductive‑medicine clinic located in Texas with dedicated treatment centers in San Antonio and Houston, specializing in assisted reproductive technologies such as In Vitro Fertilization (IVF), Intrauterine Insemination (IUI), pre‑implantation genetic testing and gender‑selection options. The clinic distinguishes itself with transparent, no‑surprise pricing, a streamlined process that reduces the typical half‑dozen pre‑treatment visits to a rapid start of care, state‑of‑the‑art laboratories, and a compassionate “fertility advocate” team that knows each patient by name. Clinical outcomes are highlighted by an IVF success rate of more than 50 percent, reflecting advances in embryo freezing, genetic testing and optimized stimulation protocols. Pozitivf’s multidisciplinary team of fertility doctors, embryologists, and support staff follows a patient‑centered, evidence‑based approach, offering free initial consultations, comprehensive insurance guidance, and extensive educational resources through an active blog covering IVF comfort, insurance options, and reproductive justice. Ongoing emotional support, flexible scheduling, and a welcoming environment aim to ease anxiety and empower patients throughout every step of their family‑building journey.

United States
star 4.8 (62)

California Fertility Clinic

Tree of Life Fertility Center is a reproductive endocrinology and infertility clinic located in the San Fernando Valley at 18370 Burbank Blvd., Suite 511, Tarzana, CA, offering over 20 years of advanced fertility care to heterosexual, LGBTIQ+, single and international patients; the center specializes in personalized, empathetic treatment and provides a full spectrum of services including intrauterine insemination (IUI), in‑vitro fertilization (IVF), reciprocal IVF (CO‑IVF), donor egg cycles, gestational carrier programs, egg and sperm cryopreservation, fertility preservation for cancer patients, tubal reversal, uterine septum correction, gender‑selection technology and comprehensive hormonal testing; its distinctive features are an inclusive environment that welcomes all family structures, a board‑certified medical team led by Dr. Vuk Jovanovic (Medical Director), Dr. S. Samuel Kim (Reproductive Endocrinology), Dr. Man Li (IVF Lab Director), Dr. Snunit Ben‑Ozer (Founder) and Caroline Kim, PA‑C, together with an experienced embryology laboratory; patient support includes free consultations, a detailed FAQ resource, personalized counseling, multilingual assistance, and ongoing education through blogs and events, all aimed at guiding patients confidently through every step of their fertility journey.

United States
star 4.8 (38)

California Dream Fertility Center

OC Fertility is a reproductive endocrinology and infertility clinic located in Aliso Viejo, California, specializing in personalized assisted reproductive technologies for individuals and couples seeking to build their families. Led by Dr. Fangyin Meng, MD, PhD—a double‑certified fertility specialist with a PhD in human embryo genetics and extensive training at Peking University and Albert‑Einstein College of Medicine—the clinic offers a full spectrum of services including comprehensive infertility evaluation, in‑vitro fertilization (IVF) with preimplantation genetic testing, intrauterine insemination (IUI), egg cryopreservation, recurrent implantation failure diagnostics, and support for single or same‑sex parents through donor and surrogacy programs. Unique features include Dr. Meng’s pioneering research in embryo genetics and endometrial receptivity, state‑of‑the‑art cryobiology labs, and a high success rate highlighted by patient testimonials praising both clinical outcomes and compassionate care. The multidisciplinary team emphasizes a personalized, evidence‑based approach, providing thorough counseling, transparent treatment planning, and continuous emotional support through on‑site coordinators, tele‑visit options, and accessible facilities with wheelchair‑friendly entrances and ample parking. OC Fertility’s commitment to patient education, rapid communication, and post‑treatment follow‑up ensures a supportive journey from the first consultation through pregnancy and beyond.

United States
star 4.8 (178)

Tree of Life Center – TLC Fertility

Tree of Life Fertility Center is a reproductive endocrinology and infertility clinic located in the San Fernando Valley at 18370 Burbank Blvd., Suite 511, Tarzana, CA, offering over 20 years of advanced fertility care to heterosexual couples, LGBTIQ+ families, singles and international patients; the center specializes in IVF, IUI, reciprocal IVF (CO‑IVF), donor‑egg cycles, gestational‑carrier programs, egg and sperm cryopreservation, fertility preservation for cancer patients, tubal reversal, gender‑selection technology and comprehensive hormonal testing, all delivered by a fully board‑certified team that includes Medical Director Dr. Vuk Jovanovic, Reproductive Endocrinology specialist Dr. S. Samuel Kim, IVF Lab Director Dr. Man Li, founder Dr. Snunit Ben‑Ozer and Certified Physician Associate Caroline Kim, PA‑C, supported by an experienced embryology laboratory; Tree of Life distinguishes itself through an empathetic, personalized approach that guarantees equal access regardless of marital status or sexual orientation, a welcoming environment that emphasizes dignity and pride, and extensive patient‑support services such as free consultations, a detailed FAQ resource, educational blog, events, and dedicated staff to guide patients through every step of their fertility journey, reflecting the clinic’s long‑standing commitment to helping families achieve pregnancy.

United States
star 4.8 (92)

Alabama Center for Reproductive Medicine (ACRM) – Montgomery

Alabama Center for Reproductive Medicine (ACRM) is a boutique fertility clinic located in Homewood, Alabama (Birmingham‑area) with an additional office in Montgomery, specializing in comprehensive reproductive care for individuals and couples seeking to build their families. Guided by board‑certified Dr. Cecil A. Long, who brings three decades of IVF, ICSI and reproductive surgery experience plus a personal IVF journey, the clinic offers a full spectrum of services including detailed fertility testing (hormone panels, semen analysis, ovarian reserve and ultrasound), ovulation induction, intrauterine insemination, in‑vitro fertilization, embryo cryopreservation using TMRW technology, minimally invasive reproductive surgery, and a weight‑loss management program to optimize fertility. A state‑of‑the‑art laboratory supports precise egg retrieval, fertilization and embryo culture, while affordable IVF options, transparent financing plans, and no age restrictions make treatment accessible. The multidisciplinary team of compassionate nurses, technicians and support staff provides personalized one‑on‑one care, early intervention for both partners, and continuous emotional support through a patient portal, resource hub, FAQs and dedicated counseling, creating a supportive community that treats each journey as a shared, hopeful experience.

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ICSI in United States

Intracytoplasmic Sperm Injection (ICSI) is an advanced IVF technique designed to overcome severe male infertility. During this procedure, a single healthy sperm is carefully selected and injected directly into the center of an egg to maximize fertilization chances. It is highly recommended for patients with low sperm count, poor motility, or previous failed IVF cycles.