Best ICSI Clinics in California
Top ICSI Clinics in California
Clinics with the highest ratings and verified quality care in this region.
Male Fertility & Sexual Medicine Specialists
Male Fertility & Sexual Medicine Specialists (MFS) is a male fertility and urology clinic located in San Diego, California, specializing in advanced vasectomy reversal and comprehensive male reproductive health; with over 30 years of excellence, the practice offers a full range of services including vasectomy reversal (both vasovasostomy and vasoepididymostomy), vasectomy, urinary incontinence treatment, erectile dysfunction therapy, Peyronie’s disease correction, sperm retrieval (including post‑mortem), male hormone replacement, and detailed fertility testing. Led by board‑certified urologist Dr. Martin Bastuba—whose microsurgical training places him among the elite 1.5 % of urologists—the team has performed more than 6,000 microsurgeries for patients from over 30 countries, achieving a reported 98 % overall patency success rate (99 % for vasovasostomies and 90 % for vasoepididymostomies) and pregnancy rates of 65‑75 % and 40‑60 % respectively. The clinic emphasizes a personalized, evidence‑based approach, transparent all‑inclusive pricing ($8,628 for reversal), complimentary consultations, travel‑planning assistance, and coordinated follow‑up care that includes pain management, recovery guidance, and a robust educational blog, ensuring international patients receive elite, cost‑effective care in a supportive environment.
Gen 5 Fertility Center
Gen 5 Fertility Center is a fertility clinic located in San Diego, CA, specializing in comprehensive assisted reproduction and ovarian rejuvenation for patients of all ages and backgrounds. Led by world‑renowned reproductive endocrinologist Dr. Samuel Wood, the center offers IVF, IUI, egg donation, egg freezing, and LGBTQIA+ family‑building services, complemented by advanced ovarian rejuvenation techniques such as platelet‑rich plasma (PRP) and EnPLAF to improve egg quality in women over 35 or those with diminished ovarian reserve. Diagnostic testing includes semen analysis, hormonal panels, FemVue HSG, hysteroscopy, laparoscopy, and minimally invasive procedures for blocked tubes, endometriosis, and fibroids, while preimplantation genetic testing ensures the healthiest embryos are transferred. The clinic’s patient‑oriented mission emphasizes compassionate, individualized care, transparent financial options, telehealth visits, and extensive support resources such as a blog, webinars, and a dedicated patient‑services team that assists with appointments, insurance navigation, and emotional counseling. By integrating cutting‑edge technology with a multidisciplinary expert team, Gen 5 Fertility Center strives to maximize each patient’s chance of a successful pregnancy and a fulfilling family‑building journey.
Hanabusa IVF
Hanabusa IVF is a fertility clinic located in San Diego, California, specializing in minimal‑stimulation and natural‑cycle IVF for patients with diminished ovarian reserve, premature ovarian failure, advanced maternal age, and high FSH levels; it also offers ovarian rejuvenation, low‑complexity IVF, and comprehensive LGBTQ+ fertility services. The center provides a personalized treatment plan that emphasizes gentle procedures, state‑of‑the‑art technology, and optimized embryo transfer, including Mini IVF, Natural Cycle IVF, simpler egg collection, and preimplantation genetic testing. Unique features include over a decade of pioneering minimal‑stimulation protocols, an innovative autologous platelet‑rich plasma ovarian rejuvenation therapy, awake egg retrieval, and an all‑inclusive approach to mental‑health support with licensed clinical social workers, acupuncture partners, and extensive patient education resources. Success is highlighted by published lab performance and embryo‑transfer outcome data for 2022‑2024, indicating competitive pregnancy rates even in challenging cases such as low AMH or extremely high FSH. The multidisciplinary team—Dr. Diana LeBlanc, Dr. Lyndon Chang, Dr. Azadeh Nezhat, NP Disha Mistri, and social‑work specialist Sheila Kubota—delivers compassionate, evidence‑based care, while patient‑support services include counseling, wellness workshops, and a robust testimonial program to guide families through every step of their fertility journey.
Incinta Fertility Center
Incinta Fertility Center is a comprehensive reproductive medicine clinic located in Torrance, California, with additional offices in Alhambra, Beverly Hills, Corona, and Irvine, specializing in advanced IVF, egg preservation, and LGBTQ family building. The center offers a full spectrum of services including in‑vitro fertilization, intrauterine insemination, secure egg freezing, fertility preservation, and personalized treatment plans supported by a Patient‑First philosophy that prioritizes each individual’s emotional and physical wellbeing. Unique features include a purpose‑built, artful and calming clinic environment, a bilingual coordination team, free virtual Fertility 101 webinars, and extensive financing options through partners such as CapexMD to remove financial barriers. Clinical excellence is highlighted by a leadership team of award‑winning physicians—Medical Directors Dr. James Lin and Dr. Omid Khorram, REI Physician Director Dr. Susan Nasab—and a laboratory directed by Dr. Yufen Xie, whose team achieved the #1 IVF success rate in the United States in 2016. The multidisciplinary staff, including a dedicated nurse manager, laboratory supervisor, and multilingual third‑party coordinator, provides continuous support, education, and compassionate care throughout the journey to parenthood.
Pearl Mini-IVF
Pearl Mini‑IVF Fertility Clinic, now operating as RMA San Diego, is a specialized reproductive medicine center located in San Diego, California, dedicated to a gentler, more holistic approach to IVF and fertility care. The clinic focuses on low‑stimulation Mini‑IVF and Natural IVF, offering traditional IVF, intrauterine insemination (IUI), diet and nutrition counseling, fertility acupuncture, and comprehensive emotional‑support services, all designed to reduce stress, cost, and health risks while maintaining success rates comparable to conventional IVF. Led by reproductive endocrinologists Dr. Haley Glatthorn Genovese and Dr. Scott J. Morin, MD, FACOG, alongside board‑certified physician assistants and embryologist Ankita Upadhye, the team provides physician‑directed monitoring and one‑on‑one patient care, distinguishing the clinic from technician‑only models. As part of the IVI RMA North America network of over 22 laboratories, Pearl Mini‑IVF benefits from cutting‑edge laboratory expertise and a collaborative, patient‑centered philosophy. Additional support includes financial coordinators, a dedicated patient portal, flexible appointment scheduling, and personalized counseling, ensuring each individual or couple receives tailored medical, nutritional, and psychological guidance throughout their fertility journey.
HRC Fertility – Rancho Cucamonga
HRC Fertility is a comprehensive reproductive medicine clinic located across multiple U.S. locations, specializing in assisted reproductive technologies and personalized family‑building solutions. With more than 35 years of experience since 1988, the center offers IVF, IUI, egg freezing, pre‑implantation genetic testing, single‑embryo transfer, LGBTQ+ family building, third‑party programs such as egg donation and surrogacy, and targeted treatments for male factor, poor ovarian reserve, and unexplained infertility. A distinctive feature is the RI Witness™ ART Management System and an in‑house infertility laboratory that safeguard samples from start to finish, while the adjacent Reproductive Surgical Associates (RSA) facility allows all diagnostics, ultrasounds and procedures to be completed in one convenient location. HRC’s success rates consistently exceed national averages, reflecting the expertise of its renowned reproductive endocrinologists who provide continuity of care from the initial consultation through obstetric graduation. The multidisciplinary team emphasizes compassionate, customized protocols and offers extensive patient support—including international concierge services via WeChat, educational seminars, webinars, a patient portal for records and billing, and dedicated LGBTQ+ resources—ensuring a seamless, supportive journey to parenthood.
Fertility & Lifespan Medical Institute
Fertility & Lifespan Medical Institute is a comprehensive reproductive medicine clinic located in San Diego, CA, specializing in integrative fertility care and lifespan health for women and men; under the leadership of Dr. Steven A. Brody, MD, PhD, the institute offers world‑class IVF at a transparent low‑cost cycle price of $5,990 that includes physician fees, monitoring, ultrasounds, egg retrieval, ICSI, embryo transfer and freezing, as well as advanced genetic testing, pre‑implantation diagnosis, egg donation, egg freezing, mini‑IVF, aggressive IVF protocols, hormonal balance programs, bioidentical hormone therapy, anti‑aging peptides, and treatment for PCOS, endometriosis, recurrent miscarriage, low sperm count, and menopausal symptoms. Unique features include San Diego’s first board‑certified program offering advanced genetic testing, a multidisciplinary team with board certifications in Internal Medicine, Endocrinology, Obstetrics‑Gynecology and Reproductive Endocrinology, and a strong emphasis on personalized, compassionate counseling that fosters long‑term patient relationships; the clinic also provides extensive patient support services such as 24/7 phone access, online appointment booking, insurance acceptance (Aetna, Cigna, Medicare, UnitedHealthcare, etc.), and educational resources through blogs and videos. While specific success rates are not listed, the institute highlights a less‑than‑2% true unexplained infertility rate and numerous patient testimonials attesting to high satisfaction and successful outcomes.
Spring Fertility
Spring Fertility Clinic is a comprehensive reproductive medicine clinic with locations in California (San Francisco – Pacific Heights and SOMA, Redwood City, Sunnyvale, Oakland, Danville), New York (Manhattan – Bryant Park, Long Island – Garden City) and Oregon (Portland), specializing in personalized IVF, IUI, egg and embryo cryopreservation, genetic counseling, LGBTQ+ care, egg donation, donor sperm and gestational carrier programs. The clinic offers a full suite of services including mental‑health support, fertility wellness counseling, donor‑tissue counseling, support groups and flexible financial options to ensure cost is not a barrier, while also hosting free community AMH testing and informational events. With a patient‑centered philosophy that blends scientific expertise with a humanistic approach, Spring’s multidisciplinary team of scientists, physicians and counselors treats each individual case creatively, as reflected in testimonials of success even in challenging scenarios and a record of over 7,571 Spring babies born. The clinic’s distinctive features include its commitment to giving back through the Spring Together Foundation and partnerships with Babies and Mothers Alive, a robust network of locations for convenient access, and a mission‑driven focus on empowering patients to achieve their family‑building goals.
Fertility & Surgical Associates of California Thousand Oaks
Fertility & Surgical Associates of California is a fertility and reproductive endocrinology clinic located in Southern California, with primary offices in Thousand Oaks, Encino and Santa Monica, specializing in comprehensive family‑building solutions that include IVF, IUI, LGBTQ donor services, fertility preservation, genetic screening and advanced diagnostic testing; the practice highlights its on‑site IVF laboratory led by a PhD embryologist, state‑of‑the‑art protocols, and a track record of remarkably high success and pregnancy rates reported by its award‑winning, board‑certified reproductive endocrinologists who see patients at every visit and conduct full one‑hour consultations to create personalized treatment plans; the multidisciplinary team of physicians, embryologists, physician assistants and registered nurses collaborates closely on each cycle, while inclusive, family‑centered care is reinforced by financing options, in‑network insurance support, a $2,000 discount on IVF Freeze‑All for self‑pay patients, 24/7 text or phone access, after‑hours answering service, and dedicated patient coordinators who guide individuals and couples through testing, treatment and emotional support, making FSAC a distinctive, high‑quality destination for those seeking successful, compassionate fertility care.
Advanced Fertility Associates
Advanced Fertility Associates Medical Group Inc is a fertility clinic located in Santa Rosa, California (4690 Hoen Ave, CA 95405), specializing in comprehensive reproductive medicine and serving as the city’s only dedicated fertility center; it offers high‑success IVF, intrauterine insemination (IUI), ovulation induction, egg and sperm donation, surrogacy, fertility preservation, reproductive surgery, andrology services, gender selection, and specialized care for cancer patients and male infertility, all supported by an on‑site laboratory. The clinic distinguishes itself with a newly expanded facility, a transparent cost‑conscious approach that includes a Kaiser patient program, a financial‑discount committee awarding $500‑$7,000 off IVF cycles, and a donated‑embryo program that leverages its high pregnancy rates to help other couples. Led by Dr. Ratcliffe and a multidisciplinary team, the practice emphasizes personalized lifestyle counseling, free diagnostic ultrasounds for new patients, and evidence‑based testing to minimize unnecessary procedures. Patient support is reinforced through a dedicated “Ask AFAMG” resource, blog education, financial‑aid applications, insurance navigation, and compassionate staff available by phone or email, ensuring affordable, effective, and empathetic care throughout every step of the fertility journey.
Fertility Specialists Medical Group
Fertility Specialists Medical Group is a reproductive medicine clinic located in San Diego and Carlsbad, California, specializing in comprehensive fertility care for female and male couples, same‑sex partners, transgender individuals and single parents, with a strong focus on IVF, IUI, egg freezing, donor‑egg programs and fertility preservation. The practice offers a full spectrum of services including personalized diagnostic work‑ups, advanced IVF and andrology laboratories, a fully accredited surgery center, and coordinated care with OB/GYNs and primary physicians, all delivered through individualized treatment plans that guide patients from initial consultation through pregnancy confirmation. Unique features include state‑of‑the‑art facilities, more than 20 years of experience, consistent recognition as a Top Doc fertility & IVF practice for over five years and an Optum Healthcare Center of Excellence for six consecutive years, underscoring high success outcomes. The multidisciplinary team, led by founder Dr. Arlene Morales and newly added Reproductive Medicine Specialist Dr. Alexa Medica, combines scientific expertise with compassionate, family‑like support, while patient‑focused services such as a 24/7 portal, free consults, research‑study participation, educational blogs and dedicated counseling ensure a seamless, supportive journey for every family‑building goal.
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ICSI in California
Intracytoplasmic Sperm Injection (ICSI) is an advanced IVF technique designed to overcome severe male infertility. During this procedure, a single healthy sperm is carefully selected and injected directly into the center of an egg to maximize fertilization chances. It is highly recommended for patients with low sperm count, poor motility, or previous failed IVF cycles.