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Infertility Center of St Louis

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About Infertility Center of St Louis

Infertility Center of St. Louis is a comprehensive reproductive medicine clinic located in St. Louis, Missouri, adjacent to St. Luke’s Hospital and a newly opened ultra‑modern IVF laboratory in a nearby suburban neighborhood, specializing in advanced IVF and fertility preservation for patients of all ages. The center offers a full spectrum of services including conventional IVF, Mini‑IVF (minimal stimulation), ICSI, TESE/MESA sperm retrieval, pre‑implantation genetic diagnosis, egg and ovary vitrification, ovary transplantation, vasectomy and tubal‑ligation reversal, PCOS management, and treatment of fibroids and adenomyosis, with lower‑cost IVF options and personalized genetic testing. Unique features include pioneering techniques pioneered by Dr. Sherman Silber—such as the world’s first microsurgical vasectomy reversal, first ovary transplant, and cutting‑edge Mini‑IVF protocols that improve success rates even for women over 40—supported by a team of internationally respected embryologists and a multidisciplinary staff that includes Dr. DeRosa and numerous academic collaborators. The clinic reports a 4.7‑star Google satisfaction rating and highlights high pregnancy success rates, especially in older patients, while providing extensive patient support through Zoom consultations, educational videos, media resources, counseling, and a best‑selling fertility guide that is reimbursed when patients choose treatment at the center.

Why choose Infertility Center of St Louis?

  • check_circle Successful Outcomes

    Patients have shared numerous success stories, with many achieving pregnancy and welcoming healthy children after treatment at the clinic. Dr. Silber's methods, especially mini IVF, are credited for achieving positive results, making this clinic a promising option for those struggling with infertility.

  • check_circle Compassionate Care

    Several reviews highlight the compassionate approach taken by Dr. Silber and his team, where staff members, including coordinators like Kelsey, provide supportive and responsive care throughout the arduous fertility journey. This patient-centered focus has made a significant difference for many families.

  • check_circle Innovative Mini IVF Technique

    The clinic is recognized for offering mini IVF, which uses fewer medications and has a lower financial burden compared to traditional IVF. This method has been effective for many older women and those seeking a more affordable path to conception.

  • check_circle Individualized Treatment Plans

    Patients have noted that Dr. Silber’s personalized approach—tailoring treatments based on individual needs—stands in stark contrast to experiences at other clinics, leading to more hopeful outcomes for patients.

  • check_circle Long-term Support

    Many parents report ongoing support from the clinic even after successful pregnancies, with the staff checking in and providing resources for future attempts, establishing lasting relationships that extend beyond treatment.

What to watch out for at Infertility Center of St Louis?

  • warning Communication Challenges

    Multiple reviews pointed out significant communication issues, particularly regarding timely information about treatment procedures, payments, and expectations. Some patients felt left in the dark after initial consultations, leading to frustrations that compounded the emotional stress of their journey.

  • warning Inconsistent Staff Engagement

    While many have praised the staff, there are stark contrasts in experiences with individuals. Some reported interactions with rude or unprofessional staff, negatively impacting their overall experience even when treatment was progressing well from a clinical standpoint.

  • warning Financial Transparency Issues

    Several clients reported dissatisfaction with the clarity of costs associated with procedures, feeling misinformed about potential fees. Unexpected charges that arose throughout the treatment process led to feelings of distrust and frustration among patients.

  • warning Limited Doctor Availability

    Patients frequently expressed disappointment in the scarce direct interaction with Dr. Silber post-consultation, leading to feelings of being overlooked and secondary to operational processes, which affected their trust in the overall experience.

  • warning Lengthy Wait Times

    Reviews indicated that patients often experienced excessive waiting times both in scheduling appointments and during visits, leading to frustration and a sense that their time was not valued. This aspect of the clinic’s operation is a common complaint among clients seeking timely care.


Infertility Center of St Louis - Patient Reviews

4.6

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madeline sti*****

3 weeks ago

star star star star star
I wouldn’t recommend coming here. It is super disheartening to hear the way Dr. Silber talks to his staff. Dr. Silber is extremely unprofessional and makes me really uncomfortable.
H

Hailey *****

1 month ago

star star star star star
This place made our dreams come true. After 6 years of infertility, we called Silber Infertility and now have a perfect little boy who is 5 months old!
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Ben Bru*****

1 month ago

star star star star star
Forever Grateful — Truly Life-Changing Care

There are not words big enough to express my wife and I's gratitude for Dr. Silber and the extraordinary people at The Infertility Center of St. Louis, who make it what it is.

From the very beginning—starting with the free Zoom consultation—we felt something rare: hope, clarity, and genuine care for us as not only humans, but shared in our mission to start a family of own. The very first conversation alone set the tone and made what once felt like an overwhelming never-ending journey feel not only possible, but medically superior.

Lauren, the New Patient Coordinator, was our very first touchpoint -- she is incredible: warm, patient with my questions, organized, promptly communicated back to us any correspondence via email, and most importantly, just deeply kind—she made us feel seen and supported from day one.

Dr. DeRosa is nothing short of brilliant. His expertise is evident immediately speaking to him, but what truly sets him apart is his superb bedside manner and extreme care for patients (so much soi he took my call on a weekend around 9pm months after transfer). He listens. He explains. He reassures. In moments, that were filled with fear and uncertainty, he brought calm and trust to a type of stress that is unique, new, and excruciating at times. Tessa and I always felt like we were in the best possible hands with his surgical expertise and overall knowledge in life and his respective field.

Julie in the financial department deserves special recognition as well. She was thoughtful, transparent, and incredibly helpful making a complex and emotional, not the cheapest process feel manageable and fair. Her kindness, layout of plans in place, and clarity lifted a weight we didn’t even realize we were carrying.

Every nurse, coordinator, and staff member treated us with dignity, empathy, and respect. At no point did we feel like a number or a new patient to bill for.

This team was truly a gift to our lives. Because of them, our family exists in a way that once felt like a distant dream. We will carry lifelong gratitude and hope to see them again soon!
A

Amanda Hi*****

1 month ago

star star star star star
Wonderful staff! Reached out through each step and answered all my questions. Dr. Silber was amazing! Even my husband loved him.
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Shanda M*****

1 month ago

star star star star star
Dr. Silber and all of his collaborative team was amazing the actual best experience I've had at a Doctor office. We have had trouble for years with infertility and Dr Silber knew exactly what he wanted me to do and when. And I can proudly say we now have a healthy, beautiful baby girl who is 3 months old. I can't say enough kind words about this office. They're a blessing.

Infertility Center of St Louis - FAQ

smart_toy AI-generated based on information from the clinic's website

Who are the fertility doctors and specialists at Infertility Center of St. Louis? expand_more
The clinical leadership at Infertility Center of St. Louis is headed by Dr. Sherman Silber, a world‑renowned reproductive endocrinologist and microsurgeon who pioneered ICSI, mini‑IVF, and egg vitrification. Dr. Silber is joined by Dr. DeRosa, his long‑time partner who also specializes in reproductive medicine and embryology. The center’s laboratory team includes senior embryologists who are recognized internationally for their technical expertise, and a dedicated microsurgery unit that performs vasectomy reversals, TESE/MESA sperm retrievals, and ovarian tissue transplantation. Together, this multidisciplinary team of fertility specialists, embryologists, and microsurgeons delivers comprehensive assisted reproduction services.
What is the history and background of Infertility Center of St. Louis? expand_more
Infertility Center of St. Louis traces its laboratory roots back to 1985, making it one of the longest‑standing IVF labs in the United States. Over the past 43 years, Dr. Sherman Silber has pioneered many of today’s standard fertility treatments, including ICSI, mini‑IVF, egg vitrification, and microscopic vasectomy reversal. The center has expanded to a new ultra‑modern IVF lab located near St. Luke’s Hospital, reinforcing its reputation as a global destination for complex infertility cases. Accreditations include high‑level clean‑room certification and continuous internal audit of clinical outcomes, reflecting a commitment to excellence and innovation.
Does Infertility Center of St. Louis offer egg donation for IVF treatment? expand_more
Yes, Infertility Center of St. Louis provides a comprehensive egg‑donation program for patients who lack viable eggs or who wish to improve their pregnancy odds. The clinic maintains a vetted donor database and typically matches recipients within three months. Donor eggs are screened for infectious diseases and genetic health, and the center offers both fresh and vitrified donor‑egg cycles. Success rates with donor‑egg IVF are comparable to the clinic’s overall IVF outcomes, benefiting from the same high‑quality laboratory environment and embryo transfer expertise.
What fertility treatments and services does Infertility Center of St. Louis offer? expand_more
Infertility Center of St. Louis provides a full spectrum of assisted reproductive technologies, including conventional IVF, Mini‑IVF, and IVF for patients over 40. Male factor solutions feature ICSI for low‑sperm or no‑sperm cases, along with microsurgical sperm retrieval (TESE/MESA). The clinic offers egg freezing, ovarian tissue cryopreservation, and donor‑egg programs with a typical three‑month matching window. Genetic testing services encompass pre‑implantation genetic diagnosis (PGD) and screening (PGS/PGTA) to detect single‑gene disorders and aneuploidy. Additional surgical options include microscopic vasectomy reversal, tubal ligation reversal, and the historic GIFT procedure for patients with intact fallopian tubes.
What IVF laboratory technology does Infertility Center of St. Louis use? expand_more
The IVF laboratory at Infertility Center of St. Louis is an ultra‑modern, clean‑room‑grade facility that operates under a highly purified air environment to protect gametes and embryos. The center pioneered the use of vitrification for egg, embryo, and ovarian tissue freezing, ensuring near‑zero ice‑crystal damage. For ICSI, the lab is the only U.S. center employing a piezo‑driven injection system, which eliminates egg trauma and maximizes fertilization rates (reported at >99% when adequate eggs are retrieved). These advanced technologies, combined with meticulous embryology protocols, support the clinic’s high fresh and frozen‑transfer success rates.
What are the IVF success rates at Infertility Center of St. Louis? expand_more
Infertility Center of St. Louis reports an overall IVF pregnancy rate of more than 60% per embryo transfer, reflecting the clinic’s emphasis on high‑quality stimulation and embryo culture. When frozen embryos from a single cycle are used, the cumulative pregnancy rate rises to approximately 94%, underscoring the effectiveness of their vitrification and thaw protocols. Success is especially notable in older patients because the center employs a Mini‑IVF protocol that yields a 4‑5‑fold higher baby‑per‑egg rate compared with conventional stimulation. These outcomes are audited internally and are consistent across fresh and frozen embryo transfers, providing patients with a reliable chance of achieving a live birth.

Contact

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Phone +1 314-576-1400
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Address 224 S Woods Mill Rd Suite 730, Chesterfield, MO 63017, USA (Find on Google Maps) open_in_new
schedule
Opening Hours
  • Monday: 9:00 AM – 5:00 PM
  • Tuesday: 9:00 AM – 5:00 PM
  • Wednesday: 9:00 AM – 5:00 PM
  • Thursday: 9:00 AM – 5:00 PM
  • Friday: 9:00 AM – 5:00 PM
  • Saturday: Closed
  • Sunday: Closed

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