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Hanabusa IVF

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San Diego, California

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Egg Donation , Genetics , ICSI , Insemination (IUI) , Natural IVF , Ovarian Rejuvenation , Social Freezing , Spermbank , Surrogacy

Open Top Rated

4.6

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About Hanabusa IVF

Hanabusa IVF is a fertility clinic located in San Diego, California, specializing in minimal‑stimulation and natural‑cycle IVF for patients with diminished ovarian reserve, premature ovarian failure, advanced maternal age, and high FSH levels; it also offers ovarian rejuvenation, low‑complexity IVF, and comprehensive LGBTQ+ fertility services. The center provides a personalized treatment plan that emphasizes gentle procedures, state‑of‑the‑art technology, and optimized embryo transfer, including Mini IVF, Natural Cycle IVF, simpler egg collection, and preimplantation genetic testing. Unique features include over a decade of pioneering minimal‑stimulation protocols, an innovative autologous platelet‑rich plasma ovarian rejuvenation therapy, awake egg retrieval, and an all‑inclusive approach to mental‑health support with licensed clinical social workers, acupuncture partners, and extensive patient education resources. Success is highlighted by published lab performance and embryo‑transfer outcome data for 2022‑2024, indicating competitive pregnancy rates even in challenging cases such as low AMH or extremely high FSH. The multidisciplinary team—Dr. Diana LeBlanc, Dr. Lyndon Chang, Dr. Azadeh Nezhat, NP Disha Mistri, and social‑work specialist Sheila Kubota—delivers compassionate, evidence‑based care, while patient‑support services include counseling, wellness workshops, and a robust testimonial program to guide families through every step of their fertility journey.

Why choose Hanabusa IVF?

check_circle Expert, Compassionate Physicians
Dr. Chang and Dr. Leblanc deliver thorough, data‑driven consultations and create customized treatment plans. Their deep knowledge and willingness to explore alternative options earn high praise, especially for patients over 40 or with complex cases.
check_circle Warm, Attentive Staff
Nurses and front‑office personnel are described as friendly, supportive, and quick to answer questions. Staff members such as Nurse Heizl, Ai, and Ryan consistently provide clear guidance and emotional reassurance.
check_circle Transparent Pricing and Flexible Payments
The clinic offers itemized cost breakdowns and charges only for services rendered, allowing patients to understand financial commitments upfront despite the cash‑only policy.
check_circle Efficient Scheduling and Minimal Wait Times
Appointments, blood draws, and ultrasounds are often scheduled within minutes, reducing stress and keeping treatment timelines on track.
check_circle Helpful Patient Portal
The online portal streamlines medication tracking, billing, and test results, making it easier for out‑of‑state patients to stay informed.

What to watch out for at Hanabusa IVF?

warning Inconsistent Communication
Critical updates, such as urgent medication orders, are sometimes delivered after office hours, leaving patients without timely guidance and forcing rushed decisions.
warning Variable Nurse Support
While many nurses are praised, some patients report rude attitudes and inadequate instruction, particularly regarding medication administration videos and demos.
warning Billing Disputes and Service Holds
Charges for unused services, such as a calcium bath, have led to account suspensions over relatively small balances, creating frustration and perceived inconsistency.
warning Limited Direct Doctor Access Post‑Consultation
After the initial visit, communication shifts to nurses, reducing direct interaction with physicians and causing uncertainty for complex questions.
warning High Cash‑Only Costs
The all‑cash model, with fees of $500 per visit and additional medication expenses, can be prohibitive for patients seeking insurance coverage.

Hanabusa IVF - Patient Reviews

4.6

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Ani*****

1 month ago

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I truly cannot say enough good things about Hanabusa IVF. My experience there from start to finish was fantastic, which I am especially grateful for considering how stressful the IVF process is to begin with. For background purposes, I was 39 with a prematurely low AMH of 0.5 when I started my IVF journey. I’d had a tubal ligation in my late 20s, because I was convinced I never wanted to have kids. I had never been pregnant, nor had I ever tried to become pregnant. When I finally did change my mind, I consulted with a clinic in L.A. that offered tubal ligation reversal surgery. They had agreed to do the surgery, and I spent several weeks trying to schedule it, only to be told that they weren’t going to do it after all because they didn’t think it was going to be successful. I decided to go the IVF route, and they told me that due to my low AMH, I would need to do mini-IVF. I knew absolutely nothing about IVF going into all of this, so I asked what the difference was between regular IVF and mini-IVF, and I was told that they just “charge less because it’s less likely to work.” After wasting nearly two months of my time at that clinic, I decided to look for a different clinic closer to me, as I live in San Diego County. That’s when I found Hanabusa. Before my consultation, I was absolutely devastated and heartbroken, convinced that I had ruined my chances of ever being able to have a child with my husband. After my consultation with Dr. LeBlanc, I felt actual hope for the first time. She explained to me in detail what exactly mini-IVF was and how it worked. She was realistic, but she was so kind and compassionate, and she made me feel like all was not lost. I really needed that. I was anxious during my entire treatment because I didn’t realize how long the process takes, nor how critical timing is. Every time I would start to panic, Dr. LeBlanc would calm me down and encourage me to be patient. Whenever she felt things were not optimal, she would tell me that she wasn’t comfortable with proceeding and that it would be beneficial to wait. She was absolutely right. She and my nurse, Kayla, patiently answered my many questions, and I felt like they really cared. Kayla would send me detailed instructions with kind words of encouragement, and she seemed genuinely happy to share good news with me. I’ll never forget the phone call I received from her letting me know that my one and only egg retrieval had yielded 2 euploid embryos (out of 5 total eggs retrieved), nor the call I received from her letting me know that the transfer was successful and my blood tests showed I was pregnant. I am now 5 months pregnant, and I couldn’t be happier. Everyone I interacted with at Hanabusa was so kind and responsive. I literally never had a bad experience with anyone there. I really don’t feel like I would have received this level of care at another clinic, especially considering the experience I had at the first one I went to. I didn’t have enough money to do more than one cycle, so I honestly believe that if not for Dr. LeBlanc’s expertise and patience, I would not be able to say that IVF worked for me.

Susana F*****

3 months ago

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Already having an IVF doctor that I was not ecstatic about I decided to try Hanabusa and I am so grateful I did. Dr. Leblanc, the nurses, the front desk, everyone that worked there made me feel right at home. Communication was awesome. Instructions were very clear and most importantly they gave me a son. I will forever be thankful for the Hanabusa Team.

Olivi*****

3 months ago

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I had a very positive experience with the clinic. The doctors and nurses were professional and caring. I would highly recommend this clinic for their support.

I had a very positive experience here. The doctors and nurses were all extremely professional, caring, and patient. They explained everything clearly and made me feel very comfortable throughout the whole process. The team is warm, attentive, and truly dedicated. I’m very grateful for their support, and I would highly recommend this clinic.

Soo*****

5 months ago

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This reviewer had a terrible experience at Hanabusa IVF clinic. They felt that the level of care and communication was poor, and that their time and emotional well-being were not respected. The clinic is also expensive and does not accept insurance.

[Warning to Anyone Considering Hanabusa] I had the absolute worst experience with Hanabusa. From start to finish, the level of care and communication has been far below any reasonable standard. I went in this morning for ultrasound and bloodwork - all done by a nurse and a technician (I’ve never met Dr. Chang aside from the initial video consult). No one explained the treatment plan, just said Dr. Chang would review results later. Around 4pm, I finally got a message in the patient portal outlining four complicated “options” as the next step. Two of the options required urgent medications, including a trigger shot. Yet no one bothered to call me to let me know I needed to pick up the medication WITHIN AN HOUR before the pharmacy closed. (The message came at 4pm, but the pharmacy they sent the prescription to closed at 5pm.) Even if I had seen it right away (which I couldn’t, because I was at work), there was absolutely no way the pharmacy could have filled it in time. On top of that, no nurse called me with instructions on how to administer the trigger shot. One of the “options” the doctor gave was basically, ‘oh well, we can just try again next cycle.’ This is beyond disrespectful. IVF is not only expensive — it’s emotionally draining. To waste an entire cycle because of the clinic’s lack of basic communication is unacceptable. And let’s not forget — this clinic takes no insurance. It’s an all-cash business. Every visit is $500 out of pocket. For that amount of money, this is absolutely not the level of care or respect I deserve. Hanabusa operates as if patients have nothing else to do but stare at their portal all day, ready to drop everything to chase down meds, and as if patients already know how to handle complex treatments without instruction. This is not patient-centered care. It’s careless, dismissive, and shows zero respect for a patient’s time, effort, or emotional well-being. Please reconsider before going here. I am sharing this to warn others so you don’t go through the same heartbreaks and frustration.

Lauren G*****

5 months ago

star star star star star

The reviewer had a successful treatment at Hanabusa IVF clinic with Dr. Chang. The clinic specializes in women over 40 and provided a personalized plan. The reviewer was grateful for the miracle baby born through this clinic.

We’re so grateful to Dr. Chang and the team at Hanabusa IVF for giving us our miracle baby girl! I'm 43 years old and after two failed egg retrievals with another clinic, we switched to Hanabusa because they specialize in women over 40, and it was the best decision we ever made. The staff is so friendly and organized, and the patient portal made it easy to track meds, instructions, and billing. The office is comfortable and inviting, where other offices made me feel like a science experiment. Dr. Chang was incredibly caring and informative, and you can tell he’s truly invested in helping you succeed. I love that he created a personalized plan for me (I was a very complicated case)... we went with less medication for higher-quality embryos, and it worked! Dr. Chang and his team were with us every step of the way, and I’ll be forever grateful for our miracle baby. No wonder he is world renowned! I feel so lucky we have him in San Diego. 5/5 stars! ⭐⭐⭐⭐⭐

Hanabusa IVF - FAQ

smart_toy AI-generated based on information from the clinic's website

What is the history and background of Hanabusa IVF? expand_more

Hanabusa IVF was founded more than a decade ago as a boutique fertility center dedicated to personalized, low‑stimulation IVF. The clinic’s origins trace back to a collaboration between Masahide Shiotani, M.D., Ph.D., founder of the renowned Hanabusa Women’s Clinic in Kobe, Japan, and Dr. Lyndon Chang, a leading pioneer of Minimal Stimulation IVF in the United States. Over the years, Hanabusa IVF has become the premier specialist in Mini IVF and Natural Cycle IVF on the West Coast. Notable milestones include the first successful autologous IVF after ovarian transplantation and the achievement of live births in women up to 49 years old using their own eggs. In the past five years, Dr. Chang has facilitated more than 25 live births for patients aged 45‑49 and over 125 live births for patients with high FSH levels, underscoring the clinic’s expertise in challenging cases such as diminished ovarian reserve and premature ovarian failure.

What fertility treatments and services does Hanabusa IVF offer? expand_more

Hanabusa IVF provides a full spectrum of assisted reproduction services tailored to each patient’s needs. Core IVF offerings include conventional In‑Vitro Fertilization (IVF), Minimal Stimulation (Mini) IVF, and Natural Cycle IVF, all designed to maximize egg quality and pregnancy rates. The clinic also offers Low Complexity IVF, which uses oral medications and local anesthesia for a simplified approach. Additional treatments include intrauterine insemination (IUI), egg freezing for fertility preservation, and comprehensive preimplantation genetic testing (PGT‑A) with embryo culture to the blastocyst stage. For patients requiring donor gametes, Hanabusa IVF runs an in‑house Asian Egg Bank with over 100 screened donors, providing both fresh and frozen donor eggs. Surrogacy coordination, reciprocal IVF for lesbian couples, and dual insemination for gay male couples are also available. Complementary services such as ovarian rejuvenation with platelet‑rich plasma, holistic IVF support, and personalized counseling round out the clinic’s extensive fertility treatment portfolio.

Does Hanabusa IVF offer egg donation for IVF treatment? expand_more

Yes, Hanabusa IVF provides a comprehensive egg donation program as part of its fertility treatment options. The clinic operates an in‑house Asian Egg Bank that features a database of more than 100 screened donors, allowing patients to select fresh or frozen donor eggs that match their genetic preferences. All donors undergo rigorous health, genetic, and infectious‑disease screening to ensure safety and high-quality donor eggs. Recipients receive individualized counseling, donor matching, and coordinated embryo creation, with the option to use preimplantation genetic testing to select the healthiest embryos for transfer. The clinic’s advanced vitrification technique ensures that frozen donor eggs retain high survival rates, contributing to strong pregnancy outcomes for recipients.

Does Hanabusa IVF provide fertility treatment for same-sex couples? expand_more

Hanabusa IVF is fully inclusive of LGBTQ+ families and offers dedicated fertility services for same‑sex couples. Lesbian partners can pursue reciprocal IVF (co‑maternity), where one partner provides the eggs and the other carries the pregnancy, with options ranging from low‑complexity oral‑medication cycles to full‑feature IVF that includes ICSI, embryo freezing, and PGT‑A. Gay male couples have access to an on‑site egg donor and surrogacy program, allowing both partners to contribute sperm to create embryos that are then transferred to a surrogate. The clinic also supports dual insemination, enabling both partners’ sperm to be used in a single cycle. All protocols are designed to maximize embryo quality, pregnancy rates, and a supportive experience for same‑sex families.

What IVF laboratory technology does Hanabusa IVF use? expand_more

Hanabusa IVF operates a state‑of‑the‑art embryology laboratory that adheres to the highest quality standards in assisted reproduction. The lab is a participant in the Progressive Laboratory Program and holds a California Tissue Bank license, FDA registration, and accreditation from the College of American Pathologists (CAP) as well as AAAASF accreditation for its procedure rooms. Embryologists employ vitrification, a flash‑freezing technique developed in Japan, to preserve embryos and oocytes with optimal survival rates. All embryos are cultured to the blastocyst stage using advanced incubators that maintain precise temperature, pH, and gas conditions, enhancing implantation potential during embryo transfer. The laboratory’s senior staff, led by Director Lisa Nelson, M.Sc., includes multiple senior embryologists and bioanalysts who ensure rigorous quality control for each step of the IVF process.

Who are the fertility doctors and specialists at Hanabusa IVF? expand_more

Hanabusa IVF is led by a team of board‑certified fertility specialists. Dr. Diana LeBlanc, MD, FACOG, is a reproductive endocrinologist with extensive experience in in‑vitro fertilization and personalized fertility treatment. Dr. Lyndon Chang, MD, FACOG, serves as Medical Director and is a pioneer of Minimal Stimulation IVF in the United States, focusing on low‑dose protocols for patients with high FSH or diminished ovarian reserve. Dr. Azadeh A. Nezhat, M.D., FACOG, is a board‑certified obstetrician‑gynecologist and minimally invasive surgeon who also contributes to the clinic’s assisted reproduction programs. The clinical team is supported by Disha Mistri, MSN, NP, a certified nurse practitioner who coordinates care for LGBTQ+ families and single patients. In the laboratory, Lisa Nelson, M.Sc., serves as Embryology Laboratory Director, overseeing embryo culture to the blastocyst stage, while senior embryologists such as Monica Velasco and Jade Yoho ensure high‑quality embryo handling. Together, this multidisciplinary group provides comprehensive IVF, embryo transfer, and fertility support.

Contact

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Phone +1 858-480-5400

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Address 4910 Directors Pl UNIT 150, San Diego, CA 92121, USA (Find on Google Maps) open_in_new

schedule

Opening Hours

Monday: 7:30 AM – 4:30 PM
Tuesday: 7:30 AM – 4:30 PM
Wednesday: 7:30 AM – 4:30 PM
Thursday: 7:30 AM – 4:30 PM
Friday: 7:30 AM – 4:30 PM
Saturday: Closed
Sunday: Closed

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