January 18, 2026

Clomid for Infertility: Essential Guidelines and Success Rates

Clomid (clomiphene citrate) offers a 10-12% pregnancy rate per cycle for infertility, with success rates influenced by age and other factors. Women under 38 can try up to six cycles, while those over 38 should consider advanced treatments after three cycles. Diagnostic tests are crucial to identify additional infertility causes like tubal disease or male factor infertility.


Key Takeaways

Clomid Success Rates by Age: What to Expect

Pregnancy rates with Clomid range from 10-12% per cycle, but outcomes decrease with age. Women over 38 have significantly lower success rates, with studies showing 87% of non-conceiving patients had additional infertility factors like endometriosis or tubal damage.

Optimal Clomid Cycle Numbers Based on Age and Ovulation Status

Women under 38 with unexplained infertility should attempt up to six Clomid cycles without ultrasound monitoring. Those over 38 require only three cycles. With ultrasound monitoring, patients under 37 may try three to four cycles, while those 37+ should transition to IVF immediately.

When to Switch from Clomid to Advanced Fertility Treatments

If Clomid fails after recommended cycles, diagnostic testing (HSG, semen analysis) is critical to identify barriers like adhesions or male infertility. 87% of non-conceiving patients had secondary infertility factors, making in vitro fertilization (IVF) the next logical step for most cases.


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